Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Am J Transplant. 2001 Nov;1(4):307-12.

Cytomegalovirus (CMV) resistance to antivirals.

Author information

  • 1Department of Laboratory Medicine, UCSF Mt. Zion Medical Center, San Francisco, CA, USA. Lawrence.Drew@clinlab.ucsfmedctr.org

Abstract

This article reviews the biology of cytomegalovirus (CMV), the approved antiviral therapies, and mechanisms of resistance to these drugs. The rates of resistance development in clinical trials are presented, as are the assays for testing susceptibility by phenotypic and genotypic methods. Factors that favor the development of clinical and in vitro antiviral resistance are discussed. Finally, approaches to altering antiviral therapy as resistance develops are outlined.

PMID:
12099372
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Blackwell Publishing
    Loading ...
    Write to the Help Desk