Total synthesis of caerulomycin C via the halogen dance reaction

Org Lett. 2002 Jul 11;4(14):2385-8. doi: 10.1021/ol026135m.

Abstract

[reaction: see text] The total synthesis of caerulomycin C is described. Key steps in this synthesis utilize 1,2-, 1,3-, and 1,4-halogen dance reactions for the functionalization of the pyridine ring.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 2,2'-Dipyridyl / analogs & derivatives
  • 2,2'-Dipyridyl / chemical synthesis*
  • Catalysis
  • Halogens / chemistry
  • Indicators and Reagents
  • Streptomyces / chemistry

Substances

  • Halogens
  • Indicators and Reagents
  • cerulomycin
  • 2,2'-Dipyridyl