Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genome Res. 2002 Jul;12(7):1075-9.

Genome size reduction through illegitimate recombination counteracts genome expansion in Arabidopsis.

Author information

  • 1John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, United Kingdom. Katrien.devos@bbsrc.ac.uk

Abstract

Genome size varies greatly across angiosperms. It is well documented that, in addition to polyploidization, retrotransposon amplification has been a major cause of genome expansion. The lack of evidence for counterbalancing mechanisms that curtail unlimited genome growth has made many of us wonder whether angiosperms have a "one-way ticket to genomic obesity." We have therefore investigated an angiosperm with a well-characterized and notably small genome, Arabidopsis thaliana, for evidence of genomic DNA loss. Our results indicate that illegitimate recombination is the driving force behind genome size decrease in Arabidopsis, removing at least fivefold more DNA than unequal homologous recombination. The presence of highly degraded retroelements also suggests that retrotransposon amplification has not been confined to the last 4 million years, as is indicated by the dating of intact retroelements.

PMID:
12097344
[PubMed - indexed for MEDLINE]
PMCID:
PMC186626
Free PMC Article

Images from this publication.See all images (1)Free text

Figure 1
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central Icon for Faculty of 1000
    Loading ...
    Write to the Help Desk