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    Clin Diagn Lab Immunol. 2002 Jul;9(4):919-20.

    In vitro assessment of antiborrelial activity of OspA vaccine sera.

    Source

    Immunology Laboratory, Department of Research, A. I. duPont Hospital for Children, Wilmington, Delaware 19803, USA. pfawcett@nemours.org

    Abstract

    Prevention of Lyme disease by the recombinant OspA-based vaccine reportedly works by preventing transmission of spirochetes from ticks to humans. We report on an in vitro microculture assay, which can be used to provide an indicator of the need for booster doses of vaccine.

    PMID:
    12093696
    [PubMed - indexed for MEDLINE]
    PMCID: PMC120022
    Free PMC Article

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