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Genome Biol. 2002;3(6):SOFTWARE0001. Epub 2002 May 23.

Software and methods for oligonucleotide and cDNA array data analysis.

Author information

  • 1The Salk Institute for Biological Studies, Laboratory of Genetics, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA. dlockhart@ambitbio.com

Abstract

Two HTML-based programs were developed to analyze and filter gene-expression data: 'Bullfrog' for Affymetrix oligonucleotide arrays and 'Spot' for custom cDNA arrays. The programs provide intuitive data-filtering tools through an easy-to-use interface. A background subtraction and normalization program for cDNA arrays was also built that provides an informative summary report with data-quality assessments. These programs are freeware to aid in the analysis of gene-expression results and facilitate the search for genes responsible for interesting biological processes and phenotypes.

PMID:
12093384
[PubMed - indexed for MEDLINE]
PMCID:
PMC139376
Free PMC Article

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