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Cancer Cell. 2002 Feb;1(1):19-30.

A matter of life and death.

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  • 1La Jolla Institute for Allergy and Immunology, 10355 Science Center Drive, San Diego, California 92121, USA.

Abstract

We propose that deregulation of proliferation, together with a reduction in apoptosis, creates a platform that is both necessary and can be sufficient for cancer. The secondary traits of diverse neoplasms are a consequence of cell proliferation, tissue expansion, and other outcomes of this platform.

PMID:
12086884
[PubMed - indexed for MEDLINE]
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