Your browser version may not work well with NCBI's Web applications. More information here...
1: Nature. 1975 Dec 18;258(5536):577-80.Links

Identification of two related pentapeptides from the brain with potent opiate agonist activity.

Enkephalin, a natural ligand for opiate receptors is composed of the pentapepides H-Tyr-Gly-Gly-Phe-Met-OH and H-Tyr-Gly-Gly-Phe-Leu-OH. The evidence is based on the determination of the amino acid sequence of natural enkephalin by the dansyl-Edman procedure and by mass spectrometry followed by synthesis and comparison of the natural and synthetic peptides.

PMID: 1207728 [PubMed - indexed for MEDLINE]