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Trends Biotechnol. 2002 Jul;20(7):277-9.

Nanostructures as tailored biological probes.

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  • 1Dept of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, MN 55455, USA.


A new generation of spectroscopic dyes is gradually becoming available to biological researchers, from an unexpected source: materials chemists who study the synthesis and properties of nano-sized inorganic objects. Research into tailoring the optical properties, surface chemistry and biocompatibility of metallic and semiconductor nanoparticles, exemplified in part by a recent report by Mirkin, Schatz and coworkers, is fulfilling the promise of these nanostructures as customizable substitutes for organic molecular probes.

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