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Dev Cell. 2002 Jun;2(6):695-706.

Convergent extension: the molecular control of polarized cell movement during embryonic development.

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  • 1Department of Molecular and Cell Biology, 401 Barker Hall, University of California, Berkeley, 94720, USA. hueco@uclink4.berkeley.edu


During development, vertebrate embryos undergo dramatic changes in shape. The lengthening and narrowing of a field of cells, termed convergent extension, contributes to a variety of morphogenetic processes. Focusing on frogs and fish, we review the different cellular mechanisms and the well-conserved signaling pathways that underlie this process.

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