Psychopharmacology (Berl). 1979;66(1):87-91.

The effect of housing and gender on preference for morphine-sucrose solutions in rats.

Hadaway PF, Alexander BK, Coambs RB, Beyerstein B.

Abstract

To determine whether opiate consumption is affected by laboratory housing, individually caged and colony rats were given a choice between water and progressively more palatable morphine-sucrose solutions. The isolated rats drank significantly more of the opiate solution, and females drank significantly more than males. In the experimental phase during which morphine-sucrose solution consumption was greatest, the isolated females drank five times as much, and the isolated males sixteen times as much morphine (mg/kg) as the colony females and males respectively.

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