Bioinformatics. 2002 May;18(5):765-6.

BeoBLAST: distributed BLAST and PSI-BLAST on a Beowulf cluster.

Grant JD, Dunbrack RL, Manion FJ, Ochs MF.

Source

Bioinformatics Facility, Fox Chase Cancer Center, Philadelphia, PA 19111, USA. jd_grant@fccc.edu

Abstract

BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through its web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work. AVAILABILITY: Source code is available under the GNU public license at http://bioinformatics.fccc.edu/

PMID:: 12050075; [PubMed - indexed for MEDLINE]

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