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Genome Biol. 2002;3(5):reviews1014. Epub 2002 Apr 25.

Targeting fragile X.

Author information

  • 1Department of Medical Genetics, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

Abstract

Ten years after the identification of the gene responsible for fragile X syndrome, recent studies have revealed a list of mRNAs bound by the fragile X gene product and have identified specific sequences required for the interaction between the fragile X protein and its targets. These results are a breakthrough in understanding why absence of the fragile X protein leads to mental retardation.

PMID:
12049671
[PubMed - indexed for MEDLINE]
PMCID:
PMC139362
Free PMC Article

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