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    Genome Biol. 2002;3(5):reviews1012. Epub 2002 Apr 15.

    Selection and gene duplication: a view from the genome.

    Wagner A.

    Department of Biology, University of New Mexico, 167A Castetter Hall, Albuquerque, NM 817131-1091, USA. wagnera@unm.edu

    Immediately after a gene duplication event, the duplicate genes have redundant functions. Is natural selection therefore completely relaxed after duplication? Does one gene evolve more rapidly than the other? Several recent genome-wide studies have suggested that duplicate genes are always under purifying selection and do not always evolve at the same rate.

    PMID: 12049669 [PubMed - indexed for MEDLINE]

    PMCID: PMC139360

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