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Microbes Infect. 2002 May;4(6):657-66.

Hepatitis E: an overview.

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  • 1Second Department of Medicine, Department of Gastroenterology and Hepatology, LKH-Universit├Ątsklinikum Graz, Auenbruggerplatz 15, Austria. harald.worm@klinikum-graz.at


The hepatitis E virus (HEV) is a non-enveloped, positive-sense, single-stranded RNA virus with icosahedral symmetry. Although it is related to the alpha-virus superfamily, the HEV is classified as a separate Hepatitis E-like viruses genus. Infection in humans occurs in sporadic and epidemic forms and can cause an acute, self-limited, icteric hepatitis. Recent studies indicate the existence of a reservoir in animals.

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