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Psychiatry Clin Neurosci. 2002 Jun;56(3):311-2.

Pulmonary hypertension in patients with severe obstructive sleep apnea.

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  • 1Sleep Disorders Center, Department of Medicine, Aichi Medical University School of Medicine, Japan.


Thirty-seven patients (35 men and two women) with obstructive sleep apnea-hypopnea syndrome (OSAHS) without any known cardiovascular and lung diseases were examined by Doppler echocardiography. Eight of the 37 (21.6%) patients experienced daytime pulmonary hypertension (PH), and all of them had severe OSAHS with an apnea-hypopnea index of > 30. The study suggested that one-third of patients with severe OSAHS had daytime PH.

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