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J Am Osteopath Assoc. 2002 May;102(5 Suppl 1):S12-4.

Practical application of Adult Treatment Panel III guidelines: three illustrative case histories.

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  • 1College of Osteopathic Medicine & Surgery in Des Moines, Iowa, USA.


The Adult Treatment Panel III (ATP III) guidelines continue to emphasize intensive treatment for persons at risk for coronary heart disease (CHD). The newest feature is a focus on primary prevention in persons with multiple risk factors; the updated guidelines recognize diabetes as a CHD risk equivalent. These groups of people already are at high risk and can benefit from increased intensive treatment to lower serum low-density lipoprotein cholesterol (LDL-C) levels. The ATP III guidelines establish lower targets for LDL-C and triglyceride levels and higher targets for the high-density lipoprotein cholesterol level. The guidelines also combine several risk factors to estimate the probability of CHD with use of the Framingham risk point-scoring formula and emphasize the multifactorial benefits of drug therapy as an adjunct to lifestyle changes.

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