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Nat Rev Cancer. 2002 May;2(5):373-82.

AIDS-related malignancies.

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  • 1Viral Oncology Group, Wolfson Institute for Biomedical Research, University College, London, UK.


Cancer remains a significant burden for human immunodeficiency virus (HIV)-infected individuals. Most cancers that are associated with HIV infection are driven by oncogenic viruses, such as Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus and human papillomavirus. Gaining insight into the epidemiology and mechanisms that underlie AIDS-related cancers has provided us with a better understanding of cancer immunity and viral oncogenesis.

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