Scanning laser ophthalmoscope-evoked multifocal-ERG (SLO-m-ERG) by using short m-sequences

Eur J Ophthalmol. 2002 Mar-Apr;12(2):109-16. doi: 10.1177/112067210201200206.

Abstract

Purpose: To demonstrate the possibility of topographic mapping of retinal function under simultaneous control of fixation in humans, by scanning laser ophthalmoscope evoked multifocal electroretinography (SLO-m-ERG).

Methods: A confocal scanning laser ophthalmoscope was used as a stimulator and trigger unit to take m-ERGs. Short m-sequences based on a modified algorithm were used, with the advantage that each measurement cycle can be evaluated separately. We examined 78 normal subjects; in 62 a distortion factor of 1:1 was applied, and a factor of 1:4 in 16.

Results: The recorded amplitudes decreased with eccentricity, approximately following the decrease of retinal cone density. Amplitudes were higher in the central hexagonal element in the group with 1:4 distortion than in the group with the 1:1 distortion setting.

Conclusions: SLO-m-ERG is a reliable technique for topographic mapping of retinal function under simultaneous control of fixation.

MeSH terms

  • Adult
  • Algorithms
  • Electroretinography / methods*
  • Humans
  • Lasers
  • Middle Aged
  • Ophthalmoscopes
  • Retina / physiology*