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Bioinformatics. 2002 Apr;18(4):631-3.

CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences.

Author information

  • 1Laboratoire de Biom├ętrie et Biologie Evolutive, UMR CNRS 5558 - Universit├ęClaude Bernard, 43, Bd du 11 Novembre 1918, 69622 Villeurbanne Cedex, France. ponger@biomserv.univ-lyon1.fr

Abstract

RESULTS:

CpGProD is an application for identifying mammalian promoter regions associated with CpG islands in large genomic sequences. Although it is strictly dedicated to this particular promoter class corresponding to approximately 50% of the genes, CpGProD exhibits a higher sensitivity and specificity than other tools used for promoter prediction. Notably, CpGProD uses different parameters according to species (human, mouse) studied. Moreover, CpGProD predicts the promoter orientation on the DNA strand.

AVAILABILITY:

http://pbil.univ-lyon1.fr/software/cpgprod.html

SUPPLEMENTARY INFORMATION:

http://pbil.univ-lyon1.fr/software/cpgprod.html

PMID:
12016061
[PubMed - indexed for MEDLINE]
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