Send to:

Choose Destination
See comment in PubMed Commons below
Appl Opt. 2002 May 1;41(13):2494-507.

Trapping forces, force constants, and potential depths for dielectric spheres in the presence of spherical aberrations.

Author information

  • 1European Molecular Biology Laboratory, Heidelberg, Germany.


We present and verify a theoretical model that predicts trapping forces (escape forces), force constants (trap stiffnesses), and trapping potential depths for dielectric spheres with diameters smaller than or equal to the wavelength of the trapping light. Optical forces can be calculated for arbitrary incident light distributions with a two-component approach that determines the gradient and the scattering force separately. We investigate the influence of spherical aberrations that are due to refractive-index mismatch on the maximum trapping force, the force constant, and the potential depth of a trap, which are important for optical tweezer applications. The relationships between the three parameters are explained and studied for different degrees of spherical aberration and various spheres (refractive indices n(s) = 1.39-1.57, radii a = 0.1-0.5 microm, lambda(0) = 1.064 microm). We find that all three parameters decrease when the distance to the coverslip increases. Effects that could make the interpretation of experimental results ambiguous are simulated and explained. Computational results are compared with the experimental data found in the literature. A good coincidence can be established.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Optical Society of America
    Loading ...
    Write to the Help Desk