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Genome Biol. 2002;3(4):REVIEWS1011. Epub 2002 Mar 27.

Genome scans and microarrays: converging on genes for schizophrenia?

Author information

  • 1Department of Psychological Medicine, Neuropsychiatric Genetics Unit, University of Wales College of Medicine, Cardiff, CF14 4XN, UK. Williamsnm@cf.ac.uk

Abstract

Systematic genome-wide scans to date have shown that genes of major effect are not common causes of schizophrenia, but independent linkage studies looking for schizophrenia susceptibility genes are converging on a number of key chromosomal locations. Microarray expression analysis may identify new candidate genes and pathways, and a number of intriguing preliminary findings have already been reported.

PMID:
11983064
[PubMed - indexed for MEDLINE]
PMCID:
PMC139350
Free PMC Article

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