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Langenbecks Arch Surg. 2002 Apr;387(1):21-6. Epub 2002 Mar 1.

Prophylactic nasal continuous positive airway pressure after major vascular surgery: results of a prospective randomized trial.

Author information

  • 1Department of Vascular Surgery and Kidney Transplantation, Heinrich-Heine University, Moorenstrasse 5, 40225 Düsseldorf, Germany. Boehner@med.uni-duesseldorf.de

Abstract

BACKGROUND:

The efficacy of nasal continuous positive airway pressure (nCPAP) as a prophylactic method for preventing cardiopulmonary complications after major vascular surgery has not been investigated.

PATIENTS/METHODS:

In a prospective randomized trial, 204 patients undergoing elective midline laparotomy for vascular surgery were randomized to receive standard therapy ( n=105) or additional prophylactic nCPAP ( n=99) for the first postoperative night. Postoperative oxygenation, incidence of severe cardiac, and pulmonary complications, length of intensive care surveillance and length of total postoperative hospital stay (LOS) were compared.

RESULTS:

Prophylactic nCPAP significantly reduced the number of patients with severe oxygenation disturbances defined as paO(2) < 70 mmHg with FiO(2) > or = 0.7 (5 versus 17, P=.01). There were no differences with respect to death, cardiac and pulmonary complications, length of intensive care surveillance or LOS.

CONCLUSION:

Prophylactic 12 h nCPAP significantly reduces the occurrence of postoperative oxygenation disturbances but has no effect on cardiac or pulmonary complications, need for intensive care, LOS or mortality after major vascular surgery.

PMID:
11981680
[PubMed - indexed for MEDLINE]
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