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    Science. 2002 Apr 12;296(5566):343-6.

    A MADS-box gene necessary for fruit ripening at the tomato ripening-inhibitor (rin) locus.

    Source

    U.S. Department of Agriculture-Agricultural Research Service (USDA-ARS) Plant, Soil and Nutrition Lab and Boyce Thompson Institute for Plant Research, Cornell University, Ithaca, NY 14853, USA.

    Abstract

    Tomato plants harboring the ripening-inhibitor (rin) mutation yield fruits that fail to ripen. Additionally, rin plants display enlarged sepals and loss of inflorescence determinacy. Positional cloning of the rin locus revealed two tandem MADS-box genes (LeMADS-RIN and LeMADS-MC), whose expression patterns suggested roles in fruit ripening and sepal development, respectively. The rin mutation alters expression of both genes. Gene repression and mutant complementation demonstrate that LeMADS-RIN regulates ripening, whereas LeMADS-MC affects sepal development and inflorescence determinacy. LeMADS-RIN demonstrates an agriculturally important function of plant MADS-box genes and provides molecular insight into nonhormonal (developmental) regulation of ripening.

    Comment in

    PMID:
    11951045
    [PubMed - indexed for MEDLINE]
    Free full text

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