Display Settings:

Format

Send to:

Choose Destination
Trends Plant Sci. 2002 Apr;7(4):153-6.

Cystathionine gamma-synthase and threonine synthase operate in concert to regulate carbon flow towards methionine in plants.

Author information

  • 1Plant Science Laboratory, Migal Galilee Technological Center, PO Box 90000, Rosh Pina 12100, Israel. rachel@migal.org.il

Abstract

The sulfur-containing amino acid methionine is a nutritionally important essential amino acid and is the precursor of several metabolites that regulate plant growth and responses to the environment. Methionine production is largely regulated by cystathionine gamma-synthase, the first specific enzyme for its synthesis. This enzyme competes in a complex manner with threonine synthase, the last enzyme in threonine biosynthesis, for their common substrate O-phosphohomoserine. New genetic and molecular data suggest that methionine synthesis and catabolism are coordinately regulated by novel post-transcriptional and post-translational mechanisms that are associated with a regulatory part within the N-terminal part of cystathionine gamma-synthase.

PMID:
11950610
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk