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Nature. 2002 Apr 11;416(6881):601-2; discussion 600, 602. Epub 2002 Apr 4.

Biodiversity (Communications arising): maize transgene results in Mexico are artefacts.

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  • 1Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA.


Quist and Chapela's conclusion that the transgenes they claim to have detected in native maize in Oaxaca, Mexico, are predominantly reassorted and inserted into a "diversity of genomic contexts" seems to be based on an artefact arising from the inverse polymerase chain reaction (i-PCR) they used to amplify sequences flanking 35S transgenes from cauliflower mosaic virus (CaMV).

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