Int J Legal Med. 2002 Feb;116(1):39-42.

Paternity testing after pregnancy termination using laser microdissection of chorionic villi.

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Institute of Legal Medicine, University of Würzburg, Germany. reme005@mail.uni-wuerzburg.de

Abstract

We report an unusual case of paternity testing from residues of chorionic villi 5 weeks after pregnancy termination. The autopsy of a 32-year-old female homicide victim revealed the presence of intact chorionic villi at the former placenta implantation site. Fetal cells were selectively isolated by laser-induced microdissection of the remaining villi to avoid contamination with maternal DNA. Simultaneous amplification of 12 STR loci in 2 PCR reactions resulted in a combined probability of paternity of 99.94%. This case demonstrates that laser-assisted microdissection and multiplex STR typing provide tools for paternity testing performed on endometrial mucosa long after the product of conception was removed by therapeutic abortion.

PMID:: 11924707; [PubMed - indexed for MEDLINE]

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Cited by 1 PubMed Central article

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