A conserved mRNA export machinery coupled to pre-m...[Cell. 2002]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 1

Click to change filter selection through MyNCBI.

1: Cell. 2002 Feb 22;108(4):523-31. Links

A conserved mRNA export machinery coupled to pre-mRNA splicing.

Reed R, Hurt E.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. robin_reed@hms.harvard.edu

Recent advances have led to a new understanding of how mRNAs are exported from the nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that is part of an elaborate machinery conserved from yeast to humans. Export of mRNAs is coupled to upstream steps in gene expression, such as pre-mRNA splicing, and to downstream events, including nonsense-mediated decay.

PMID: 11909523 [PubMed - indexed for MEDLINE]

ReviewNuclear mRNA binding proteins couple pre-mRNA splicing and post-splicing events.
Mol Cells. 2001 Aug 31; 12(1):1-10.

[Mol Cells. 2001]
ReviewA new view of mRNA export: separating the wheat from the chaff.
Nat Cell Biol. 2001 Sep; 3(9):E201-4.

[Nat Cell Biol. 2001]
The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans.
Nature. 2000 Sep 21; 407(6802):401-5.

[Nature. 2000]
YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA.
Mol Cell. 2007 Feb 23; 25(4):559-73.

[Mol Cell. 2007]
Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm.
Mol Cell. 2000 Sep; 6(3):673-82.

[Mol Cell. 2000]
» See reviews... | » See all...

Cited by 63 PubMed Central articles

Multipotent genetic suppression of retrotransposon-induced mutations by Nxf1 through fine-tuning of alternative splicing.
Concepcion D, Flores-García L, Hamilton BA. PLoS Genet. 2009 May; 5(5):e1000484. Epub 2009 May 15.

[PLoS Genet. 2009]
Targeting tat inhibitors in the assembly of human immunodeficiency virus type 1 transcription complexes.
D'Orso I, Grunwell JR, Nakamura RL, Das C, Frankel AD. J Virol. 2008 Oct; 82(19):9492-504. Epub 2008 Jul 30.

[J Virol. 2008]
Imaging and characterizing influenza A virus mRNA transport in living cells.
Wang W, Cui ZQ, Han H, Zhang ZP, Wei HP, Zhou YF, Chen Z, Zhang XE. Nucleic Acids Res. 2008 Sep; 36(15):4913-28. Epub 2008 Jul 24.

[Nucleic Acids Res. 2008]
» See all...

Recent Activity

Clear Turn Off Turn On

A conserved mRNA export machinery coupled to pre-mRNA splicing.A conserved mRNA export machinery coupled to pre-mRNA splicing.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

A conserved mRNA export machinery coupled to pre-mRNA splicing.

Related articles

Cited by 63 PubMed Central articles

Recent Activity