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Nat Prod Rep. 2002 Feb;19(1):70-99.

Biosynthesis and attachment of novel bacterial polyketide synthase starter units.

Moore BS, Hertweck C.

Division of Medicinal Chemistry, College of Pharmacy, University of Arizona, Tucson 85721-0207, USA. moore@pharmacy.arizona.edu

The biosynthesis and mode of attachment of a wide range of polyketide synthase (PKS) starter units in bacteria are covered in this review. Natural, unnatural, and engineered starter units associated with type I and type II PKSs are reported. The literature through early 2001 is reviewed, and 240 references cited.

PMID: 11902441 [PubMed - indexed for MEDLINE]

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