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Antimicrob Agents Chemother. 2002 Apr;46(4):1147-52.

Novel type of staphylococcal cassette chromosome mec identified in community-acquired methicillin-resistant Staphylococcus aureus strains.

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  • 1Department of Bacteriology, Juntendo University, Tokyo, Japan.

Abstract

We identified a new type of staphylococcal cassette chromosome mec (SCCmec) from two community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strains. The novel element, designated type IV SCCmec, had a unique combination of the class B mec gene complex and the type 2 ccr gene complex and was much smaller in size (21 to 24 kb) than previously identified SCCmec elements of hospital-acquired MRSA. Consistent with the strains' susceptibilities to various non-beta-lactam antibiotics, the type IV SCCmec was devoid of any antibiotic resistance genes other than the mecA gene.

PMID:
11897611
PMCID:
PMC127097
[PubMed - indexed for MEDLINE]
Free PMC Article
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