Structure of rhodopsin and the superfamily of seve...[Curr Opin Cell Biol. 2002]

SearchDatabase nameforSearch term

Advanced Search

Your browser version may not work well with NCBI's Web applications. More information here...

Display Show

All: 1

Review: 1

Click to change filter selection through MyNCBI.

1: Curr Opin Cell Biol. 2002 Apr;14(2):189-95. Links

Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same.

Sakmar TP.

Howard Hughes Medical Institute, Laboratory of Molecular Biology and Biochemistry, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA. sakmar@mail.rockefeller.edu

The crystal structure of rhodopsin provides significant insights concerning structure/activity relationships in visual pigments and related G-protein-coupled receptors. The specific arrangement of seven-transmembrane helices is stabilized by a series of intermolecular interactions that appear to be conserved among Family A receptors. However, the potential for structural and functional diversity among members of the superfamily of seven-helical receptors presents a significant future challenge.

PMID: 11891118 [PubMed - indexed for MEDLINE]

Studies on the structure of the G-protein-coupled receptor rhodopsin including the putative G-protein binding site in unactivated and activated forms.
Biochemistry. 2001 Oct 2; 40(39):11932-7.

[Biochemistry. 2001]
ReviewActivation of rhodopsin: new insights from structural and biochemical studies.
Trends Biochem Sci. 2001 May; 26(5):318-24.

[Trends Biochem Sci. 2001]
Structures of the transmembrane helices of the G-protein coupled receptor, rhodopsin.
J Pept Res. 2001 Jul; 58(1):79-89.

[J Pept Res. 2001]
Light-activated rhodopsin induces structural binding motif in G protein alpha subunit.
Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4270-5.

[Proc Natl Acad Sci U S A. 1998]
ReviewRhodopsin: insights from recent structural studies.
Annu Rev Biophys Biomol Struct. 2002; 31:443-84. Epub 2001 Oct 25.

[Annu Rev Biophys Biomol Struct. 2002]
» See reviews... | » See all...

Cited by 8 PubMed Central articles

ReviewG protein coupled receptor structure and activation.
Kobilka BK. Biochim Biophys Acta. 2007 Apr; 1768(4):794-807. Epub 2006 Nov 15.

[Biochim Biophys Acta. 2007]
ReviewG protein-coupled receptor rhodopsin.
Palczewski K. Annu Rev Biochem. 2006; 75:743-67.

[Annu Rev Biochem. 2006]
Trans fatty acid derived phospholipids show increased membrane cholesterol and reduced receptor activation as compared to their cis analogs.
Niu SL, Mitchell DC, Litman BJ. Biochemistry. 2005 Mar 22; 44(11):4458-65.

[Biochemistry. 2005]
» See all...

Recent Activity

Clear Turn Off Turn On

Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not th...Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same.

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Display Show

Structure of rhodopsin and the superfamily of seven-helical receptors: the same and not the same.

Related articles

Cited by 8 PubMed Central articles

Recent Activity