Abstract
The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Bacterial Proteins*
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Chemotaxis*
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Gene Deletion
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Genes, Bacterial*
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Genetic Complementation Test
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Immunoblotting
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Membrane Proteins / analysis
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Membrane Proteins / genetics
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Membrane Proteins / metabolism*
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Methyl-Accepting Chemotaxis Proteins
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Vibrio cholerae / metabolism*
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Vibrio cholerae / pathogenicity
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Virulence
Substances
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Bacterial Proteins
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Membrane Proteins
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Methyl-Accepting Chemotaxis Proteins