Analyses of the roles of the three cheA homologs in chemotaxis of Vibrio cholerae

J Bacteriol. 2002 Mar;184(6):1767-71. doi: 10.1128/JB.184.6.1767-1771.2002.

Abstract

The Vibrio cholerae genome revealed the presence of multiple sets of chemotaxis genes, including three cheA gene homologs. We found that the cheA-2, but not cheA-1 or cheA-3, gene is essential for chemotaxis under standard conditions. Loss of chemotaxis had no effect on virulence factor expression in vitro.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins*
  • Chemotaxis*
  • Gene Deletion
  • Genes, Bacterial*
  • Genetic Complementation Test
  • Immunoblotting
  • Membrane Proteins / analysis
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism*
  • Methyl-Accepting Chemotaxis Proteins
  • Vibrio cholerae / metabolism*
  • Vibrio cholerae / pathogenicity
  • Virulence

Substances

  • Bacterial Proteins
  • Membrane Proteins
  • Methyl-Accepting Chemotaxis Proteins