Curr Pain Headache Rep. 2002 Apr;6(2):151-5.

Should butalbital-containing analgesics be banned? Yes.

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Jefferson Headache Center, Department of Neurology, Thomas Jefferson University, 111 South 11th Street, Philadelphia, PA 19107, USA. William.B.Young@mail.tju.edu

Abstract

In the United States analgesic-overuse headache is often caused by butalbital-containing analgesics. These agents can cause physical and psychological dependency, and dangerous withdrawal syndromes. Butalbital-containing analgesics have already been banned in several European countries. They are proven effective in tension-type headache, but not in migraine; there are many alternative treatments for migraine and tension-type headache. In the 20 years since analgesic overuse headache was widely recognized, butalbital overuse has remained distressingly common. It is time to ban these agents.

PMID:: 11872187; [PubMed - indexed for MEDLINE]

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Chemical compound information

butalbital

MW: 224.25 g/mol

MF: C₁₁H₁₆N₂O₃

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