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1: Curr Pain Headache Rep. 2002 Apr;6(2):147-50.Links

Butalbital-containing agents: should they be banned? No.

Solomon S.

Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA. sysol@earthlink.net

Butalbital compounds are of proven efficacy in the treatment of tension headache. Decades of experience have established their value in the treatment of other mild-to-moderate headaches. Untold numbers of people rely on these medications as their drug of choice or use them when vasoconstrictors, opioids, or nonsteroidal anti-inflammatory agents are contraindicated. The medications are cost-effective with only occasional and minor immediate adverse effects. Their overuse may cause the evolution of episodic primary headaches to chronic daily headaches; however, removal of these agents from the market would reduce the chronic daily headache in the general population by a small fraction of 1%.

PMID: 11872186 [PubMed - indexed for MEDLINE]