Herpes. 2001 Nov;8(3):76-9.

Serological testing for human herpesvirus 8.

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Clinic of Infectious Diseases, Department of Public Health, Tor Vergata University, Rome, Italy. sarmati@med.uniroma2.it

Abstract

Human herpesvirus 8 (HHV-8) has been identified in skin lesions of patients with Kaposi's sarcoma and is now considered a co-factor for the development of the neoplasm associated with this disease. Several laboratory tests are currently available for use in the detection of HHV-8 antibodies--immunofluorescence and enzyme-linked immunosorbant assays being the most frequently used tests. Epidemiological studies have demonstrated the existence of hyperendemic regions where HHV-8 infection is ubiquitous and often acquired early in childhood. The role of HHV-8 in the development of Kaposi's sarcoma has yet to be clarified completely and data collected from the epidemiological studies of HHV-8 prevalence may be useful in gaining a better understanding of the different factors involved in tumour development.

PMID:: 11867024; [PubMed - indexed for MEDLINE]

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