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1: Genome Biol. 2002;3(2):COMMENT2001. Epub 2002 Jan 31.Click here to read Click here to read Links

The past, present and future of genome-wide re-annotation.

Ouzounis CA, Karp PD.

Bioinformatics Research Group, AI Center, SRI International, Menlo Park, CA 94025, USA. pkarp@ai.sri.com

Annotation, the process by which structural or functional information is inferred for genes or proteins, is crucial for obtaining value from genome sequences. We define the process of annotating a previously annotated genome sequence as 're-annotation', and examine the strengths and weaknesses of current manual and automatic genome-wide re-annotation approaches.

PMID: 11864365 [PubMed - indexed for MEDLINE]

PMCID: PMC139008