Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Dev Genes Evol. 2001 Dec;211(11):555-8. Epub 2001 Nov 23.

Gdf5 is expressed in the developing skeleton of median fins of late-stage zebrafish, Danio rerio.

Author information

  • 1Department of Biology, University of South Dakota, Vermillion, SD 57069, USA.

Abstract

The dynamic expression of Gdf5 is described in the developing skeleton of the median fins of late-stage zebrafish, Danio rerio (6-45 days post-fertilization). In situ hybridization revealed expression in the mesenchyme between cartilage condensations of the endoskeletal supports of the dorsal, anal, and caudal fins. As development proceeds, the expression domains expand distally to surround tips of developing cartilages, consistent with a role in cartilage growth and differentiation. Gdf5 is later expressed in the segmenting regions of the dorsal and anal fin radials, which may indicate a role in segmentation. After growth to 7.5 mm, Gdf5 transcripts can no longer be detected in any of the median fins, nor is Gdf5 expression reinitiated in later development of the median fin skeleton.

PMID:
11862461
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Write to the Help Desk