Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
    Curr Opin Neurobiol. 2002 Feb;12(1):49-56.

    Neurodevelopmental control by thyroid hormone receptors.

    Source

    Department of Human Genetics, Mount Sinai School of Medicine, 1425 Madison Avenue, New York, New York 10029, USA. douglas.forrest@mssm.edu

    Abstract

    Recent studies have provided insights into the neurodevelopmental functions of thyroid hormone signaling. The nuclear thyroid hormone receptors (TRs) are ligand-activated transcription factors and a variety of TR isotypes, generated by two genes, mediate distinct processes. In addition, deiodinase enzymes that regulate levels of the main active form of thyroid hormone, T3, are likely to cooperate closely with TRs in specifying a localized and timely response to thyroid hormones in target tissues. Some of the most sensitive processes controlled by these pathways are in the auditory and visual sensory systems.

    PMID:
    11861164
    [PubMed - indexed for MEDLINE]

      Supplemental Content

      Icon for Elsevier Science

      Save items

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk