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[A case - control study of gallstone disease in female population in Taicang].

[Article in Chinese]

Author information

  • 1Department of Epidemiology, Beijing Medical University, Beijing 100083, China.



To investigate the risk factors of gallstone disease in female population in Taicang.


A case - control study conducted on 144 cases and 371 controls aged 35 - 79 years in five villages. Diagnosis of gallstone disease was assessed by real - time ultrasonography. The case was considered as presence of gallstones at echograph and previous cholecytectomy. The controls were selected from a random sample of female participates.


Through univariate and multivariate analysis, gallstone disease was significantly associated with age (OR = 1.80), family history of gallstone disease (OR = 3.66), hypertension (OR = 1.93), fat intake (OR = 1.77), number of pregnancies (OR = 1.44) and menopause (OR = 1.67). Drinking water from deep well (OR = 0.54) was inversely associated with gallstone disease.


The main risk factors of female gallstone disease were age, family history of gallstone disease, fat intake, number of pregnancy and menopause. Drinking water from deep well was a protective factor of gallstone disease.

[PubMed - indexed for MEDLINE]
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