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Zhonghua Xue Ye Xue Za Zhi. 2001 Nov;22(11):581-3.

[The effectiveness of cyclosporin A in the treatment of autoimmune hemolytic anemia and Evans syndrome].

[Article in Chinese]

Author information

  • 1Institute of Hematology and Blood Diseases Hospital, CAMS & PUMC, Tianjin 300020, China.

Abstract

OBJECTIVE:

To test the therapeutic effectiveness of cyclosporin A (CsA) in combination with corticosteroid in the treatment of autoimmune hemolytic anemia(AIHA) and Evans syndrome.

METHODS:

Forty-four cases of AIHA and Evans syndrome were treated with CsA in combination with a conventional regimen (prednisone + danazol) (18 cases) or conventional regimen alone(26 cases).

RESULTS:

The complete response rate of CsA group (88.9%) was higher than that of conventional regimen group (57.7%) (P < 0.05), and the relapse rate was lower (3.3% vs 70%) (P < 0.01).

CONCLUSION:

CsA in combination with conventional regimen can improve the complete response rate and reduce relapse of AIHA and Evans syndrome.

PMID:
11855146
[PubMed - indexed for MEDLINE]
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