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Bioinformatics. 2002 Jan;18(1):198-9.

Dragon Promoter Finder: recognition of vertebrate RNA polymerase II promoters.

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  • 1BIC-KRDL, Kent Ridge Digital Laboratories, 21, Heng Mui Keng Terrace, Singapore 119613. bajicv@krdl.org.sg


Dragon Promoter Finder (DPF) locates RNA polymerase II promoters in DNA sequences of vertebrates by predicting Transcription Start Site (TSS) positions. DPF's algorithm uses sensors for three functional regions (promoters, exons and introns) and an Artificial Neural Network (ANN). Results on a large and diverse evaluation set indicate that DPF exhibits a superior predicting ability for TSS location compared to three other promoter-finding programs.

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