Role of the B7-CD28/CTLA-4 pathway in autoimmune d...[Curr Dir Autoimmun. 2002]

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1: Curr Dir Autoimmun. 2002;5:113-30.Links

Role of the B7-CD28/CTLA-4 pathway in autoimmune disease.

Chang TT, Kuchroo VK, Sharpe AH.

Immunology Research Division, Department of Pathology, Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass., USA.

PMID: 11826754 [PubMed - indexed for MEDLINE]

ReviewComplexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation.
Annu Rev Immunol. 2001; 19:225-52.

[Annu Rev Immunol. 2001]
B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.
Immunity. 2000 Apr; 12(4):431-40.

[Immunity. 2000]
Interference with CD28, CD80, CD86 or CD152 in collagen-induced arthritis. Limited role of IFN-gamma in anti-B7-mediated suppression of disease.
J Autoimmun. 2001 Aug; 17(1):39-50.

[J Autoimmun. 2001]
B7 interactions with CD28 and CTLA-4 control tolerance or induction of mucosal inflammation in chronic experimental colitis.
J Immunol. 2001 Aug 1; 167(3):1830-8.

[J Immunol. 2001]
ReviewThe expanding world of co-stimulation: the two-signal model revisited.
Trends Immunol. 2001 Apr; 22(4):217-23.

[Trends Immunol. 2001]
» See reviews... | » See all...

Cited by 1 PubMed Central article

Interferon-beta up-regulates the expression of co-stimulatory molecules CD80, CD86 and CD40 on monocytes: significance for treatment of multiple sclerosis.
Marckmann S, Wiesemann E, Hilse R, Trebst C, Stangel M, Windhagen A. Clin Exp Immunol. 2004 Dec; 138(3):499-506.

[Clin Exp Immunol. 2004]

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