Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Clin Pathol. 2002 Jan;55(1):76-7.

Microinvasive lobular carcinoma associated with intraductal spread arising in a mammary hamartoma.

Author information

  • 1First Department of Pathology, Kochi Medical School, Kohasu, Oko-cho, Nankoku City, Kochi 783-8505, Japan. nkuroda@kochi-ms.ac.up

Abstract

A 53 year old woman presented with a lump in the inner lower quadrant of the left breast. Histological examination of the breast tumour confirmed that the lesion was a mammary hamartoma. Carcinoma with foci of microinvasion was observed in the lobules of the hamartoma concomitant with the intraductal spread of lobular carcinoma. Immunohistochemically, the cancer cells were negative for beta-catenin, which generally stained normal breast ducts and ductal carcinomas. This is only the sixth case of breast carcinoma arising in a mammary hamartoma to be reported and, moreover, the fourth case of lobular carcinoma occurring within a hamartoma. Despite the apparent rarity of this case, pathologists should be aware of the possibility of carcinomas arising within mammary hamartomas.

PMID:
11825932
[PubMed - indexed for MEDLINE]
PMCID:
PMC1769570
Free PMC Article

Images from this publication.See all images (2)Free text

Figure 1
Figure 2
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk