Abstract
A novel resveratrol tetramer, vaticanol C, isolated from the stem bark of Vatica rassak markedly suppressed cell growth through induction of apoptosis, which was characterized by nuclear changes and DNA ladder formation, in three different human colon cancer cell lines.
MeSH terms
-
Antineoplastic Agents, Phytogenic / pharmacology*
-
Apoptosis / drug effects*
-
Colonic Neoplasms / drug therapy*
-
DNA, Neoplasm / drug effects
-
Humans
-
Molecular Weight
-
Plant Epidermis / chemistry
-
Resveratrol
-
Stilbenes / pharmacology*
-
Tumor Cells, Cultured
Substances
-
Antineoplastic Agents, Phytogenic
-
DNA, Neoplasm
-
Stilbenes
-
vaticanol C
-
Resveratrol