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Nat Rev Neurosci. 2002 Jan;3(1):65-71.

Neurogenesis in adult primate neocortex: an evaluation of the evidence.

Author information

  • Pasko Rakic is at the Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. pasko.rakic@yale.edu


Reports of continuous genesis and turnover of neurons in the adult primate association neocortex--the site of the highest cognitive functions--have generated great excitement. Here, I review the available evidence, and question the scientific basis of this claim.

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