Send to

Choose Destination
See comment in PubMed Commons below
Science. 2002 Feb 1;295(5556):813-8.

Signal transduction and the control of gene expression.

Author information

  • 1Laboratory of Molecular Vertebrate Embryology, Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.


More than 2000 transcription factors are encoded in the human genome. Such proteins have often been classified according to common structural elements. But because transcription factors evolved in the service of biologic function, we propose an alternative grouping of eukaryotic transcription factors on the basis of characteristics that describe their roles within cellular regulatory circuits.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk