Background: The rate of transmission of HIV and other sexually transmitted infections from female to female is a matter of debate. Sexually transmitted disease among lesbians and female bisexuals is usually associated with sexual contact with men or intravenous drug use. There is little evidence that female-to-female transmission of syphilis can occur.
Goals: To demonstrate that female-to-female transmission of syphilis can occur through oral-genital sex.
Study design: Case report of syphilis transmission from one female to another through oral-genital sex.
Conclusion: Female-to-female transmission of syphilis can occur through oral-genital sex.