The effect of indigenous Neem Azadirachta indica [correction of (Adirachta indica)] mouth wash on Streptococcus mutans and lactobacilli growth

Indian J Dent Res. 2001 Jul-Sep;12(3):133-44.

Abstract

Neem is one of the most widely researched tropical tree, with almost all it's parts being put for a variety of uses. In the present study, the antibacterial effect of Neem mouthwash against salivary levels of streptococcus mutans and lactobacillus has been tested over a period of 2 months. Also it's effect in reversing incipient carious lesions was assessed. While streptococcus mutans was inhibited by Neem mouthwashes, with or without alcohol as well as chlorhexidine, lactobacillus growth was inhibited by chlorhexidine alone. The initial data appears to prove it's effect in inhibiting S. mutans and reversing incipient carious lesions, longer term clinical trials are essential.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Anti-Infective Agents, Local / therapeutic use*
  • Child
  • Chlorhexidine / administration & dosage
  • Chlorhexidine / therapeutic use
  • Colony Count, Microbial
  • Dental Caries / prevention & control
  • Dental Prophylaxis
  • Ethanol / therapeutic use
  • Follow-Up Studies
  • Glycerides / administration & dosage
  • Glycerides / therapeutic use*
  • Humans
  • India
  • Lactobacillus / drug effects*
  • Lactobacillus / growth & development
  • Mouthwashes / therapeutic use*
  • Pharmaceutical Vehicles
  • Placebos
  • Plant Oils / administration & dosage
  • Plant Oils / therapeutic use*
  • Plants, Medicinal / chemistry*
  • Saliva / microbiology
  • Statistics, Nonparametric
  • Streptococcus mutans / drug effects*
  • Streptococcus mutans / growth & development
  • Terpenes / administration & dosage
  • Terpenes / therapeutic use*
  • Trees / chemistry

Substances

  • Anti-Infective Agents, Local
  • Glycerides
  • Mouthwashes
  • Pharmaceutical Vehicles
  • Placebos
  • Plant Oils
  • Terpenes
  • Ethanol
  • neem oil
  • Chlorhexidine