A case-control study involving 242 women with histologically confirmed lung cancer and 352 healthy controls, was conducted in Cracow, Poland between 1991 and 1997. Subjects were interviewed about their exposure to smoking, passive smoking and other suspected risk factors, according to a structured questionnaire. Multivariate analysis has shown that cigarette smoking was the most strongly active risk factor in female lung cancer. The strongest influence of this factor was observed with reference to small cell carcinoma and squamous cell carcinoma. It has also been observed that passive smoking exposure during childhood before the age of 18, significantly increased risk of squamous cell carcinoma, small cell carcinoma and all cell types combined. A similar effect was observed for adenocarcinoma, but there was no statistical significance.