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Trends Neurosci. 2002 Jan;25(1):5-6.

Glial processes are glued to synapses via Ca(2+)-permeable glutamate receptors.

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  • 1Dept of Anatomy, Hokkaido University School of Medicine, 060-8638, Sapporo, Japan. watamasa@med.hokudai.ac.jp

Abstract

Bergmann glia in the cerebellum elaborately ensheathe Purkinje cell dendrites and synapses, and express high levels of Ca(2+)-permeable glutamate receptors (GluRs). Suppression of the Ca(2+) permeability by virus-mediated GluR2 transfer has revealed that GluR-mediated Ca(2+) signaling is essential to maintain both structural and functional connections between the glial cell and the glutamatergic synapses.

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PMID:
11801322
[PubMed - indexed for MEDLINE]
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