Psychosom Med. 1975 May-Jun;37(3):245-64.

Studies on how early maternal separation produces behavioral change in young rats.

Abstract

Previously published studies point to the behavioral interaction between the mother and her litter as the origin of the processes responsible for the behavioral hyperactivity following maternal separation in 2-week-old rats. The following experiments explore (1) the time course over which behavioral hyperactivity develops, (2) environmental and social determinants, (3) the role of sensory stimulation in the regulation of behavior and (4) the olfactory sensory system as a mediator of separation effects. The hypotheses supported best by the data are (1) that tactile and olfactory stimulation repeatedly provided by the mother act to reduce levels of behavioral arousal of the infants and (2) that maternal separation exerts its effect by withdrawal of this regulating influence, allowing a new level of behavioral arousal, more intrinsic to the infant, to be revealed.

PMID:: 1178795; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms

Publication Types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH Terms

LinkOut - more resources

Full Text Sources

HighWire Press - PDF

Supplemental Content

Save items

Related citations in PubMed

Maternal and littermate deprivation disrupts maternal behavior and social-learning of food preference in adulthood: tactile stimulation, nest odor, and social rearing prevent these effects. [Dev Psychobiol. 2006]
Maternal and littermate deprivation disrupts maternal behavior and social-learning of food preference in adulthood: tactile stimulation, nest odor, and social rearing prevent these effects.
Melo AI, Lovic V, Gonzalez A, Madden M, Sinopoli K, Fleming AS. Dev Psychobiol. 2006 Apr; 48(3):209-19.
Temporal and social factors influencing behavioral and hormonal responses to separation in mother and infant squirrel monkeys. [Psychoneuroendocrinology. 1993]
Temporal and social factors influencing behavioral and hormonal responses to separation in mother and infant squirrel monkeys.
Levine S, Wiener SG, Coe CL. Psychoneuroendocrinology. 1993; 18(4):297-306.
Total cortisol, free cortisol, and growth hormone associated with brief social separation experiences in young macaques. [Dev Psychobiol. 1995]
Total cortisol, free cortisol, and growth hormone associated with brief social separation experiences in young macaques.
Laudenslager ML, Boccia ML, Berger CL, Gennaro-Ruggles MM, McFerran B, Reite ML. Dev Psychobiol. 1995 May; 28(4):199-211.
Review Responses to maternal separation: mechanisms and mediators. [Int J Dev Neurosci. 1998]
Review Responses to maternal separation: mechanisms and mediators.
Kuhn CM, Schanberg SM. Int J Dev Neurosci. 1998 Jun-Jul; 16(3-4):261-70.
Review Olfactory regulation of maternal behavior in mammals. [Horm Behav. 2004]
Review Olfactory regulation of maternal behavior in mammals.
Lévy F, Keller M, Poindron P. Horm Behav. 2004 Sep; 46(3):284-302.

See reviews... See all...

Cited by 3 PubMed Central articles

Adolescent female rats are more resistant than males to the effects of early stress on prefrontal cortex and impulsive behavior. [Dev Psychobiol. 2009]
Adolescent female rats are more resistant than males to the effects of early stress on prefrontal cortex and impulsive behavior.
Spivey JM, Shumake J, Colorado RA, Conejo-Jimenez N, Gonzalez-Pardo H, Gonzalez-Lima F. Dev Psychobiol. 2009 Apr; 51(3):277-88.
Physical stimulation reduces the brain temperature of infant rats. [Dev Psychobiol. 1988]
Physical stimulation reduces the brain temperature of infant rats.
Sullivan RM, Wilson DA, Leon M. Dev Psychobiol. 1988 Apr; 21(3):237-50.
Physical stimulation reduces the body temperature of infant rats. [Dev Psychobiol. 1988]
Physical stimulation reduces the body temperature of infant rats.
Sullivan RM, Shokrai N, Leon M. Dev Psychobiol. 1988 Apr; 21(3):225-35.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Studies on how early maternal separation produces behavioral change in young rat...
Studies on how early maternal separation produces behavioral change in young rats.
Psychosom Med. 1975 May-Jun ;37(3):245-64.

PubMed
The relationship between self-reported and clinical measures and the number of d...
The relationship between self-reported and clinical measures and the number of days to return to sport following acute lateral ankle sprains.
J Orthop Sports Phys Ther. 2002 Jan ;32(1):16-23.

PubMed
The prognostic factors of adult tuberculous meningitis.
The prognostic factors of adult tuberculous meningitis.
Infection. 2001 Dec ;29(6):299-304.

PubMed
Role of residual insulin secretion in protecting against ketoacidosis in insulin...
Role of residual insulin secretion in protecting against ketoacidosis in insulin-dependent diabetes.
Br Med J. 1979 Nov 17 ;2(6200):1257-9.

PubMed
Neural aspects of prostaglandin involvement in gastric mucosal defense.
Neural aspects of prostaglandin involvement in gastric mucosal defense.
J Physiol Pharmacol. 2001 Dec ;52(4 Pt 1):555-68.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

Studies on how early maternal separation produces behavioral change in young rats.

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Full Text Sources

Supplemental Content

Save items

Related citations in PubMed

Cited by 3 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information